India is dealing with the second wave of Coronavirus. Many people have died and the Indian government is keeping all its efforts to control the spread of coronavirus. According to the reports, the second wave of COVID-19 is coming down and most of the countries want to vaccinate the people of their nations to save the lives of vulnerable groups as some of the experts are anticipating a third wave of COVID-19.
There is a huge demand for the vaccine and the supply of vaccine is less. The scientists are trying their best to come up with the new vaccines so as to put an end to this dangerous coronavirus. An antibody nasal spray is one of the things that scientists are studying. They have created a hybrid antibody that is found to be capable of reducing the amount of SARS-CoV-2 in the lungs of infected mice.
According to a study published in journal Nature, “The nasal spray of a designer antibody offers protection against variants of coronavirus in mice. The team of researchers led by Zhiqiang Ku, an antibody engineer at the University of Texas Health Science Center, are working to engineer an antibody that can be delivered directly into the nose.”
The team scanned a library of antibodies and found the one that could recognise a component of SARS-CoV-2 that the virus utilises to latch on to and penetrate cells in order to produce the antibody. It included immunoglobulin M (IgM) that was specifically designed to the invading pathogen, SARS-CoV-2.
According to a Nature report, “The team stitched segments of IgG targeting SARS-CoV-2 to a new sort of molecule, IgM antibodies, which act as quick first-responders to a wide range of infections. The modified antibody demonstrated a greater rate of neutralising action against more than 20 Covid-19 variations.”